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        news Acute Pancreatitis Associated to the Use of Valproic Acid

        Presented by:Arquivos de Neuro-Psiquiatria / Guevara-Campos, José, González-Guevara, Lucía, Vacaro-Bolívar, Ixora and Rojas, Juan Manuel
        Summary points:A 7-year-old girl with generalised epilepsy taking valproic acid 15 mg/kg/day presents with abdominal pain localised in the epigastrium, which was not alleviated by the administration of common antispasmodic type analgesics, and fever. Medical and family history, physical examination, laboratory data, abdominal ultrasonography, electroencephalogram, and abdominal computed axial tomography are described. The authors advise paediatricians and neurologists to consider pancreatitis, a difficult-to-diagnose complication, when a child receiving treatment with valproic acid shows gastrointestinal symptoms.
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